STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NSD1Nuclear receptor binding SET domain protein 1. (2426 aa)    
Predicted Functional Partners:
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.720
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
    
 0.696
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
    
 0.696
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.687
LOC103221971
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.685
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
  
 0.639
NUP98
Nucleoporin 98.
   
 0.634
NSD3
Nuclear receptor binding SET domain protein 3.
    
 
 0.624
MDC1
Mediator of DNA damage checkpoint 1.
   
 0.622
PRDM2
PR/SET domain 2.
   
 0.617
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.