| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APBB1 | APLP2 | ENSCSAP00000000662 | ENSCSAP00000015845 | Amyloid beta precursor protein binding family B member 1. | Amyloid beta precursor like protein 2. | 0.900 |
| APBB1 | APP | ENSCSAP00000000662 | ENSCSAP00000005302 | Amyloid beta precursor protein binding family B member 1. | Amyloid beta precursor protein. | 0.972 |
| APBB1 | BACE1 | ENSCSAP00000000662 | ENSCSAP00000015359 | Amyloid beta precursor protein binding family B member 1. | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.488 |
| APBB1 | NAE1 | ENSCSAP00000000662 | ENSCSAP00000000950 | Amyloid beta precursor protein binding family B member 1. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.524 |
| APLP2 | APBB1 | ENSCSAP00000015845 | ENSCSAP00000000662 | Amyloid beta precursor like protein 2. | Amyloid beta precursor protein binding family B member 1. | 0.900 |
| APLP2 | APOE | ENSCSAP00000015845 | ENSCSAP00000014799 | Amyloid beta precursor like protein 2. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.792 |
| APLP2 | APP | ENSCSAP00000015845 | ENSCSAP00000005302 | Amyloid beta precursor like protein 2. | Amyloid beta precursor protein. | 0.972 |
| APLP2 | BACE1 | ENSCSAP00000015845 | ENSCSAP00000015359 | Amyloid beta precursor like protein 2. | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.738 |
| APLP2 | CLU | ENSCSAP00000015845 | ENSCSAP00000012055 | Amyloid beta precursor like protein 2. | Clusterin; Belongs to the clusterin family. | 0.716 |
| APLP2 | NAE1 | ENSCSAP00000015845 | ENSCSAP00000000950 | Amyloid beta precursor like protein 2. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.522 |
| APLP2 | PSEN1 | ENSCSAP00000015845 | ENSCSAP00000008949 | Amyloid beta precursor like protein 2. | Presenilin 1. | 0.642 |
| APLP2 | SNCA | ENSCSAP00000015845 | ENSCSAP00000000583 | Amyloid beta precursor like protein 2. | Alpha-synuclein; Belongs to the synuclein family. | 0.705 |
| APLP2 | SORL1 | ENSCSAP00000015845 | ENSCSAP00000015606 | Amyloid beta precursor like protein 2. | Sortilin related receptor 1. | 0.838 |
| APOE | APLP2 | ENSCSAP00000014799 | ENSCSAP00000015845 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Amyloid beta precursor like protein 2. | 0.792 |
| APOE | APP | ENSCSAP00000014799 | ENSCSAP00000005302 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Amyloid beta precursor protein. | 0.977 |
| APOE | BACE1 | ENSCSAP00000014799 | ENSCSAP00000015359 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Beta-secretase 1; Belongs to the peptidase A1 family. | 0.490 |
| APOE | CLU | ENSCSAP00000014799 | ENSCSAP00000012055 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Clusterin; Belongs to the clusterin family. | 0.788 |
| APOE | PSEN1 | ENSCSAP00000014799 | ENSCSAP00000008949 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Presenilin 1. | 0.769 |
| APOE | SNCA | ENSCSAP00000014799 | ENSCSAP00000000583 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Alpha-synuclein; Belongs to the synuclein family. | 0.928 |
| APOE | SORL1 | ENSCSAP00000014799 | ENSCSAP00000015606 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Sortilin related receptor 1. | 0.856 |
