STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRPM5Transient receptor potential cation channel subfamily M member 5. (1170 aa)    
Predicted Functional Partners:
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 
 0.756
TRPV2
Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family.
   
 
 0.754
TRPV5
Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family.
   
 
 0.742
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.725
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
   
 
 0.643
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
   
  
 0.640
GNA14
G protein subunit alpha 14.
    
 
 0.636
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
   
 
 0.633
POU2F3
POU domain protein.
    
 
 0.632
MCTP2
Multiple C2 and transmembrane domain containing 2.
   
  
 0.622
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.