ICOS protein (Chlorocebus sabaeus) - STRING interaction network

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[Homology]

Score

ICOS

Inducible T cell costimulator. (192 aa)

Predicted Functional Partners:

ICOSLG

0.999

PIK3R1

0.981

CD40LG

0.977

PIK3CB

0.964

PIK3CA

0.964

PIK3CD

0.962

PIK3R2

0.961

PIK3R3

0.961

CD4

0.876

CTLA4

0.866

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	CD40LG	ENSCSAP00000006497	ENSCSAP00000003738	CD4 molecule.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.900
CD4	CTLA4	ENSCSAP00000006497	ENSCSAP00000006517	CD4 molecule.	Cytotoxic T-lymphocyte associated protein 4.	0.920
CD4	ICOS	ENSCSAP00000006497	ENSCSAP00000006510	CD4 molecule.	Inducible T cell costimulator.	0.876
CD4	ICOSLG	ENSCSAP00000006497	ENSCSAP00000004143	CD4 molecule.	Uncharacterized protein.	0.615
CD40LG	CD4	ENSCSAP00000003738	ENSCSAP00000006497	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD4 molecule.	0.900
CD40LG	CTLA4	ENSCSAP00000003738	ENSCSAP00000006517	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Cytotoxic T-lymphocyte associated protein 4.	0.605
CD40LG	ICOS	ENSCSAP00000003738	ENSCSAP00000006510	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Inducible T cell costimulator.	0.977
CD40LG	ICOSLG	ENSCSAP00000003738	ENSCSAP00000004143	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.479
CTLA4	CD4	ENSCSAP00000006517	ENSCSAP00000006497	Cytotoxic T-lymphocyte associated protein 4.	CD4 molecule.	0.920
CTLA4	CD40LG	ENSCSAP00000006517	ENSCSAP00000003738	Cytotoxic T-lymphocyte associated protein 4.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.605
CTLA4	ICOS	ENSCSAP00000006517	ENSCSAP00000006510	Cytotoxic T-lymphocyte associated protein 4.	Inducible T cell costimulator.	0.866
CTLA4	ICOSLG	ENSCSAP00000006517	ENSCSAP00000004143	Cytotoxic T-lymphocyte associated protein 4.	Uncharacterized protein.	0.945
CTLA4	PIK3CA	ENSCSAP00000006517	ENSCSAP00000009123	Cytotoxic T-lymphocyte associated protein 4.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.588
CTLA4	PIK3CB	ENSCSAP00000006517	ENSCSAP00000007336	Cytotoxic T-lymphocyte associated protein 4.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.544
CTLA4	PIK3CD	ENSCSAP00000006517	ENSCSAP00000017236	Cytotoxic T-lymphocyte associated protein 4.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.546
CTLA4	PIK3R1	ENSCSAP00000006517	ENSCSAP00000011965	Cytotoxic T-lymphocyte associated protein 4.	Phosphoinositide-3-kinase regulatory subunit 1.	0.818
CTLA4	PIK3R2	ENSCSAP00000006517	ENSCSAP00000001700	Cytotoxic T-lymphocyte associated protein 4.	Uncharacterized protein.	0.520
CTLA4	PIK3R3	ENSCSAP00000006517	ENSCSAP00000016789	Cytotoxic T-lymphocyte associated protein 4.	Phosphoinositide-3-kinase regulatory subunit 3.	0.520
ICOS	CD4	ENSCSAP00000006510	ENSCSAP00000006497	Inducible T cell costimulator.	CD4 molecule.	0.876
ICOS	CD40LG	ENSCSAP00000006510	ENSCSAP00000003738	Inducible T cell costimulator.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.977

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