| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDNF | EGFR | ENSCSAP00000018826 | ENSCSAP00000012126 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Receptor protein-tyrosine kinase. | 0.712 |
| BDNF | FLT1 | ENSCSAP00000018826 | ENSCSAP00000013989 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.741 |
| BDNF | MET | ENSCSAP00000018826 | ENSCSAP00000007132 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | MET proto-oncogene, receptor tyrosine kinase. | 0.705 |
| BDNF | NGFR | ENSCSAP00000018826 | ENSCSAP00000015601 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Nerve growth factor receptor. | 0.973 |
| BDNF | NTF3 | ENSCSAP00000018826 | ENSCSAP00000007186 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.693 |
| BDNF | NTRK1 | ENSCSAP00000018826 | ENSCSAP00000015828 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Tyrosine-protein kinase receptor. | 0.970 |
| BDNF | NTRK2 | ENSCSAP00000018826 | ENSCSAP00000003745 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neurotrophic receptor tyrosine kinase 2. | 0.998 |
| BDNF | NTRK3 | ENSCSAP00000018826 | ENSCSAP00000013241 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Tyrosine-protein kinase receptor. | 0.917 |
| BDNF | PDGFRA | ENSCSAP00000018826 | ENSCSAP00000001309 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.762 |
| BDNF | RET | ENSCSAP00000018826 | ENSCSAP00000007188 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.718 |
| EGFR | BDNF | ENSCSAP00000012126 | ENSCSAP00000018826 | Receptor protein-tyrosine kinase. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.712 |
| EGFR | FLT1 | ENSCSAP00000012126 | ENSCSAP00000013989 | Receptor protein-tyrosine kinase. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.456 |
| EGFR | MET | ENSCSAP00000012126 | ENSCSAP00000007132 | Receptor protein-tyrosine kinase. | MET proto-oncogene, receptor tyrosine kinase. | 0.946 |
| EGFR | NTF3 | ENSCSAP00000012126 | ENSCSAP00000007186 | Receptor protein-tyrosine kinase. | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.721 |
| EGFR | NTRK1 | ENSCSAP00000012126 | ENSCSAP00000015828 | Receptor protein-tyrosine kinase. | Tyrosine-protein kinase receptor. | 0.420 |
| EGFR | NTRK2 | ENSCSAP00000012126 | ENSCSAP00000003745 | Receptor protein-tyrosine kinase. | Neurotrophic receptor tyrosine kinase 2. | 0.818 |
| EGFR | PDGFRA | ENSCSAP00000012126 | ENSCSAP00000001309 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.974 |
| EGFR | RET | ENSCSAP00000012126 | ENSCSAP00000007188 | Receptor protein-tyrosine kinase. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.828 |
| FLT1 | BDNF | ENSCSAP00000013989 | ENSCSAP00000018826 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.741 |
| FLT1 | EGFR | ENSCSAP00000013989 | ENSCSAP00000012126 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Receptor protein-tyrosine kinase. | 0.456 |
