Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
MRASMuscle RAS oncogene homolog. (208 aa)    
Predicted Functional Partners:
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.989
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.986
SHOC2
SHOC2 leucine rich repeat scaffold protein.
    
 0.981
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.972
ENSCSAP00000011134
Uncharacterized protein.
    
 0.971
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.965
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.965
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.965
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.963
RAPGEF5
Rap guanine nucleotide exchange factor 5.
    
 0.959
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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