STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRASHRas proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.998
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.997
RASA1
RAS p21 protein activator 1.
   
 0.996
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.989
RASSF5
Ras association domain family member 5.
    
 0.989
PIK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.988
AFDN
Afadin, adherens junction formation factor.
    
 0.985
RASGRP4
RAS guanyl releasing protein 4.
    
 0.981
EGFR
Receptor protein-tyrosine kinase.
   
 0.977
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.975
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.