Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL2Cullin 2; Belongs to the cullin family. (842 aa)    
Predicted Functional Partners:
RBX1
Ring-box 1.
    
 0.999
ELOC
Elongin C; Belongs to the SKP1 family.
   
 0.999
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.996
VHL
Von Hippel-Lindau tumor suppressor.
    
 0.995
ELOB
Ubiquitin-like domain-containing protein.
    
 0.989
ENSCSAP00000018734
Ubiquitin-like domain-containing protein.
    
 0.989
UBXN7
UBX domain protein 7.
   
 0.984
CAND1
Cullin associated and neddylation dissociated 1.
    
 0.977
EPAS1
Endothelial PAS domain protein 1.
    
 0.977
COPS5
COP9 signalosome subunit 5.
   
 0.968
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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