| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COP1 | CUL4A | ENSCSAP00000008170 | ENSCSAP00000013471 | COP1 E3 ubiquitin ligase. | Cullin 4A; Belongs to the cullin family. | 0.974 |
| COP1 | CUL4B | ENSCSAP00000008170 | ENSCSAP00000014347 | COP1 E3 ubiquitin ligase. | Cullin 4B; Belongs to the cullin family. | 0.924 |
| COP1 | DDB1 | ENSCSAP00000008170 | ENSCSAP00000002685 | COP1 E3 ubiquitin ligase. | Damage specific DNA binding protein 1. | 0.978 |
| COP1 | DDB2 | ENSCSAP00000008170 | ENSCSAP00000002004 | COP1 E3 ubiquitin ligase. | Damage specific DNA binding protein 2. | 0.975 |
| COP1 | DET1 | ENSCSAP00000008170 | ENSCSAP00000013234 | COP1 E3 ubiquitin ligase. | Uncharacterized protein. | 0.986 |
| COP1 | ERCC8 | ENSCSAP00000008170 | ENSCSAP00000012124 | COP1 E3 ubiquitin ligase. | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. | 0.949 |
| COP1 | RBX1 | ENSCSAP00000008170 | ENSCSAP00000002157 | COP1 E3 ubiquitin ligase. | Ring-box 1. | 0.941 |
| COP1 | TP53 | ENSCSAP00000008170 | ENSCSAP00000007551 | COP1 E3 ubiquitin ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.982 |
| COP1 | TRIB1 | ENSCSAP00000008170 | ENSCSAP00000006362 | COP1 E3 ubiquitin ligase. | Tribbles pseudokinase 1. | 0.930 |
| COP1 | TRIB3 | ENSCSAP00000008170 | ENSCSAP00000009031 | COP1 E3 ubiquitin ligase. | Tribbles pseudokinase 3. | 0.921 |
| CUL4A | COP1 | ENSCSAP00000013471 | ENSCSAP00000008170 | Cullin 4A; Belongs to the cullin family. | COP1 E3 ubiquitin ligase. | 0.974 |
| CUL4A | CUL4B | ENSCSAP00000013471 | ENSCSAP00000014347 | Cullin 4A; Belongs to the cullin family. | Cullin 4B; Belongs to the cullin family. | 0.999 |
| CUL4A | DDB1 | ENSCSAP00000013471 | ENSCSAP00000002685 | Cullin 4A; Belongs to the cullin family. | Damage specific DNA binding protein 1. | 0.999 |
| CUL4A | DDB2 | ENSCSAP00000013471 | ENSCSAP00000002004 | Cullin 4A; Belongs to the cullin family. | Damage specific DNA binding protein 2. | 0.990 |
| CUL4A | DET1 | ENSCSAP00000013471 | ENSCSAP00000013234 | Cullin 4A; Belongs to the cullin family. | Uncharacterized protein. | 0.921 |
| CUL4A | ERCC8 | ENSCSAP00000013471 | ENSCSAP00000012124 | Cullin 4A; Belongs to the cullin family. | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. | 0.987 |
| CUL4A | RBX1 | ENSCSAP00000013471 | ENSCSAP00000002157 | Cullin 4A; Belongs to the cullin family. | Ring-box 1. | 0.995 |
| CUL4A | TP53 | ENSCSAP00000013471 | ENSCSAP00000007551 | Cullin 4A; Belongs to the cullin family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.665 |
| CUL4B | COP1 | ENSCSAP00000014347 | ENSCSAP00000008170 | Cullin 4B; Belongs to the cullin family. | COP1 E3 ubiquitin ligase. | 0.924 |
| CUL4B | CUL4A | ENSCSAP00000014347 | ENSCSAP00000013471 | Cullin 4B; Belongs to the cullin family. | Cullin 4A; Belongs to the cullin family. | 0.999 |
