| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CIAO1 | CIAO2A | ENSCSAP00000013405 | ENSCSAP00000008611 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | FeS_assembly_P domain-containing protein. | 0.935 |
| CIAO1 | CIAO2B | ENSCSAP00000013405 | ENSCSAP00000000939 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 2B. | 0.990 |
| CIAO1 | CIAO3 | ENSCSAP00000013405 | ENSCSAP00000008336 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. | 0.945 |
| CIAO1 | CIAPIN1 | ENSCSAP00000013405 | ENSCSAP00000001234 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.562 |
| CIAO1 | ENSCSAP00000017448 | ENSCSAP00000013405 | ENSCSAP00000017448 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | FeS_assembly_P domain-containing protein. | 0.903 |
| CIAO1 | ISCU | ENSCSAP00000013405 | ENSCSAP00000015165 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.717 |
| CIAO1 | LYRM4 | ENSCSAP00000013405 | ENSCSAP00000003582 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Uncharacterized protein; Belongs to the complex I LYR family. | 0.526 |
| CIAO1 | MMS19 | ENSCSAP00000013405 | ENSCSAP00000002170 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.991 |
| CIAO1 | NFS1 | ENSCSAP00000013405 | ENSCSAP00000006543 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Aminotran_5 domain-containing protein. | 0.710 |
| CIAO1 | NUBP1 | ENSCSAP00000013405 | ENSCSAP00000004712 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Nucleotide binding protein 1. | 0.639 |
| CIAO2A | CIAO1 | ENSCSAP00000008611 | ENSCSAP00000013405 | FeS_assembly_P domain-containing protein. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | 0.935 |
| CIAO2A | CIAO2B | ENSCSAP00000008611 | ENSCSAP00000000939 | FeS_assembly_P domain-containing protein. | Cytosolic iron-sulfur assembly component 2B. | 0.712 |
| CIAO2A | CIAO3 | ENSCSAP00000008611 | ENSCSAP00000008336 | FeS_assembly_P domain-containing protein. | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. | 0.899 |
| CIAO2A | ISCU | ENSCSAP00000008611 | ENSCSAP00000015165 | FeS_assembly_P domain-containing protein. | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.514 |
| CIAO2A | LYRM4 | ENSCSAP00000008611 | ENSCSAP00000003582 | FeS_assembly_P domain-containing protein. | Uncharacterized protein; Belongs to the complex I LYR family. | 0.428 |
| CIAO2A | MMS19 | ENSCSAP00000008611 | ENSCSAP00000002170 | FeS_assembly_P domain-containing protein. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.873 |
| CIAO2A | NFS1 | ENSCSAP00000008611 | ENSCSAP00000006543 | FeS_assembly_P domain-containing protein. | Aminotran_5 domain-containing protein. | 0.448 |
| CIAO2B | CIAO1 | ENSCSAP00000000939 | ENSCSAP00000013405 | Cytosolic iron-sulfur assembly component 2B. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | 0.990 |
| CIAO2B | CIAO2A | ENSCSAP00000000939 | ENSCSAP00000008611 | Cytosolic iron-sulfur assembly component 2B. | FeS_assembly_P domain-containing protein. | 0.712 |
| CIAO2B | CIAO3 | ENSCSAP00000000939 | ENSCSAP00000008336 | Cytosolic iron-sulfur assembly component 2B. | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. | 0.909 |
