| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHCY | DNMT1 | ENSCSAP00000008298 | ENSCSAP00000003647 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.920 |
| AHCY | DNMT3A | ENSCSAP00000008298 | ENSCSAP00000004839 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.912 |
| AHCY | DNMT3B | ENSCSAP00000008298 | ENSCSAP00000008720 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.917 |
| AHCY | GNMT | ENSCSAP00000008298 | ENSCSAP00000007708 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Glycine N-methyltransferase. | 0.949 |
| AHCY | MAT1A | ENSCSAP00000008298 | ENSCSAP00000005644 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.703 |
| AHCY | MAT2A | ENSCSAP00000008298 | ENSCSAP00000012240 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.662 |
| DNMT1 | AHCY | ENSCSAP00000003647 | ENSCSAP00000008298 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.920 |
| DNMT1 | DNMT3A | ENSCSAP00000003647 | ENSCSAP00000004839 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.994 |
| DNMT1 | DNMT3B | ENSCSAP00000003647 | ENSCSAP00000008720 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.999 |
| DNMT1 | DNMT3L | ENSCSAP00000003647 | ENSCSAP00000004106 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | PHD-type domain-containing protein. | 0.753 |
| DNMT1 | ENSCSAP00000004852 | ENSCSAP00000003647 | ENSCSAP00000004852 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Uncharacterized protein. | 0.964 |
| DNMT1 | EZH2 | ENSCSAP00000003647 | ENSCSAP00000003315 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Enhancer of zeste 2 polycomb repressive complex 2 subunit. | 0.980 |
| DNMT1 | GNMT | ENSCSAP00000003647 | ENSCSAP00000007708 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Glycine N-methyltransferase. | 0.936 |
| DNMT1 | MAT1A | ENSCSAP00000003647 | ENSCSAP00000005644 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.907 |
| DNMT1 | MAT2A | ENSCSAP00000003647 | ENSCSAP00000012240 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.911 |
| DNMT1 | MAT2B | ENSCSAP00000003647 | ENSCSAP00000006477 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.923 |
| DNMT3A | AHCY | ENSCSAP00000004839 | ENSCSAP00000008298 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.912 |
| DNMT3A | DNMT1 | ENSCSAP00000004839 | ENSCSAP00000003647 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.994 |
| DNMT3A | DNMT3B | ENSCSAP00000004839 | ENSCSAP00000008720 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.902 |
| DNMT3A | DNMT3L | ENSCSAP00000004839 | ENSCSAP00000004106 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | PHD-type domain-containing protein. | 0.919 |
