STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)    
Predicted Functional Partners:
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.995
DNMT3L
PHD-type domain-containing protein.
  
 
0.979
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
 
 
0.973
ENSCSAP00000004852
Uncharacterized protein.
 
 
 0.949
MAT2A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.946
AHCY
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
     
 0.912
MAT1A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.911
AHCYL2
Adenosylhomocysteinase like 2; Belongs to the adenosylhomocysteinase family.
     
 0.903
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
     
 0.903
AMD1
Adenosylmethionine decarboxylase 1.
     
  0.900
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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