| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HGS | STAM | ENSCSAP00000015796 | ENSCSAP00000008819 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule. | 0.999 |
| HGS | STAM2 | ENSCSAP00000015796 | ENSCSAP00000012093 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule 2. | 0.999 |
| HGS | TSG101 | ENSCSAP00000015796 | ENSCSAP00000001374 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | UBAP1 | ENSCSAP00000015796 | ENSCSAP00000006260 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin associated protein 1. | 0.933 |
| HGS | VPS28 | ENSCSAP00000015796 | ENSCSAP00000004690 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.968 |
| HGS | VPS37A | ENSCSAP00000015796 | ENSCSAP00000012830 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37A subunit of ESCRT-I. | 0.930 |
| JAK2 | JAK3 | ENSCSAP00000005088 | ENSCSAP00000001784 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK2 | STAM | ENSCSAP00000005088 | ENSCSAP00000008819 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.947 |
| JAK2 | STAM2 | ENSCSAP00000005088 | ENSCSAP00000012093 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.945 |
| JAK2 | TYK2 | ENSCSAP00000005088 | ENSCSAP00000003507 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.984 |
| JAK3 | JAK2 | ENSCSAP00000001784 | ENSCSAP00000005088 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| JAK3 | STAM | ENSCSAP00000001784 | ENSCSAP00000008819 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.953 |
| JAK3 | STAM2 | ENSCSAP00000001784 | ENSCSAP00000012093 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.959 |
| JAK3 | TYK2 | ENSCSAP00000001784 | ENSCSAP00000003507 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.950 |
| STAM | HGS | ENSCSAP00000008819 | ENSCSAP00000015796 | Signal transducing adaptor molecule. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.999 |
| STAM | JAK2 | ENSCSAP00000008819 | ENSCSAP00000005088 | Signal transducing adaptor molecule. | Tyrosine-protein kinase. | 0.947 |
| STAM | JAK3 | ENSCSAP00000008819 | ENSCSAP00000001784 | Signal transducing adaptor molecule. | Tyrosine-protein kinase. | 0.953 |
| STAM | STAM2 | ENSCSAP00000008819 | ENSCSAP00000012093 | Signal transducing adaptor molecule. | Signal transducing adaptor molecule 2. | 0.996 |
| STAM | STAMBP | ENSCSAP00000008819 | ENSCSAP00000011589 | Signal transducing adaptor molecule. | STAM binding protein. | 0.995 |
| STAM | TSG101 | ENSCSAP00000008819 | ENSCSAP00000001374 | Signal transducing adaptor molecule. | Tumor susceptibility 101. | 0.961 |
