Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNB3Cyclin B3; Belongs to the cyclin family. (1324 aa)    
Predicted Functional Partners:
CDK1
Protein kinase domain-containing protein.
   
 0.979
PLK1
Serine/threonine-protein kinase PLK.
   
 0.974
CDC25A
Cell division cycle 25A.
   
 0.960
SFN
Stratifin; Belongs to the 14-3-3 family.
    
 0.932
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 
0.926
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 
0.926
GADD45A
Growth arrest and DNA damage inducible alpha.
    
 0.922
GADD45G
Growth arrest and DNA damage inducible gamma.
    
 0.919
GADD45B
Growth arrest and DNA damage inducible beta.
    
 0.910
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.842
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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