| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GCDH | UBE2E3 | ENSCSAP00000002824 | ENSCSAP00000009087 | Glutaryl-CoA dehydrogenase. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.873 |
| OTUB1 | TRIP12 | ENSCSAP00000003177 | ENSCSAP00000003303 | Ubiquitin thioesterase. | Thyroid hormone receptor interactor 12. | 0.673 |
| OTUB1 | UBA1 | ENSCSAP00000003177 | ENSCSAP00000009833 | Ubiquitin thioesterase. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.428 |
| OTUB1 | UBE2E1 | ENSCSAP00000003177 | ENSCSAP00000006016 | Ubiquitin thioesterase. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.856 |
| OTUB1 | UBE2E3 | ENSCSAP00000003177 | ENSCSAP00000009087 | Ubiquitin thioesterase. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.828 |
| PRKN | TMEM189-UBE2V1 | ENSCSAP00000008452 | ENSCSAP00000011175 | Parkin RBR E3 ubiquitin protein ligase. | TMEM189-UBE2V1 readthrough. | 0.755 |
| PRKN | UBE2E1 | ENSCSAP00000008452 | ENSCSAP00000006016 | Parkin RBR E3 ubiquitin protein ligase. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.683 |
| PRKN | UBE2E3 | ENSCSAP00000008452 | ENSCSAP00000009087 | Parkin RBR E3 ubiquitin protein ligase. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.825 |
| RNF25 | UBE2E1 | ENSCSAP00000005025 | ENSCSAP00000006016 | Ring finger protein 25. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.615 |
| RNF25 | UBE2E3 | ENSCSAP00000005025 | ENSCSAP00000009087 | Ring finger protein 25. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.814 |
| RNF5 | UBE2E1 | ENSCSAP00000005552 | ENSCSAP00000006016 | Ring finger protein 5. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.478 |
| RNF5 | UBE2E3 | ENSCSAP00000005552 | ENSCSAP00000009087 | Ring finger protein 5. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.859 |
| RNF8 | TMEM189-UBE2V1 | ENSCSAP00000006706 | ENSCSAP00000011175 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | TMEM189-UBE2V1 readthrough. | 0.670 |
| RNF8 | TRIP12 | ENSCSAP00000006706 | ENSCSAP00000003303 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | Thyroid hormone receptor interactor 12. | 0.501 |
| RNF8 | UBE2E1 | ENSCSAP00000006706 | ENSCSAP00000006016 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.721 |
| RNF8 | UBE2E3 | ENSCSAP00000006706 | ENSCSAP00000009087 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.846 |
| TMEM189-UBE2V1 | PRKN | ENSCSAP00000011175 | ENSCSAP00000008452 | TMEM189-UBE2V1 readthrough. | Parkin RBR E3 ubiquitin protein ligase. | 0.755 |
| TMEM189-UBE2V1 | RNF8 | ENSCSAP00000011175 | ENSCSAP00000006706 | TMEM189-UBE2V1 readthrough. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.670 |
| TMEM189-UBE2V1 | TRIP12 | ENSCSAP00000011175 | ENSCSAP00000003303 | TMEM189-UBE2V1 readthrough. | Thyroid hormone receptor interactor 12. | 0.507 |
| TMEM189-UBE2V1 | UBA1 | ENSCSAP00000011175 | ENSCSAP00000009833 | TMEM189-UBE2V1 readthrough. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.686 |
