STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC25CCell division cycle 25C. (474 aa)    
Predicted Functional Partners:
CHEK1
Checkpoint kinase 1.
   
 0.943
CDK1
Protein kinase domain-containing protein.
   
 0.935
PLK1
Serine/threonine-protein kinase PLK.
   
 0.929
ENSCSAP00000006204
FHA domain-containing protein.
   
 0.921
YWHAZ
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.919
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 0.900
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.861
CHEK2
Protein kinase domain-containing protein.
   
 0.832
WEE1
Wee1-like protein kinase.
   
 0.796
PLK3
Serine/threonine-protein kinase PLK.
   
 0.791
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.