STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)    
Predicted Functional Partners:
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.997
CBL
Cbl proto-oncogene.
    
 0.997
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.984
ABL1
Tyrosine-protein kinase.
    
0.984
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.981
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.980
GAB1
GRB2 associated binding protein 1.
    
 0.979
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.978
ABL2
Tyrosine-protein kinase.
    
0.964
EGFR
Receptor protein-tyrosine kinase.
    
 0.964
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.