STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE3TLE family member 3, transcriptional corepressor. (769 aa)    
Predicted Functional Partners:
FOXA1
Forkhead box A1.
    
 0.750
TLE1
TLE family member 1, transcriptional corepressor.
  
 
0.735
LEF1
Lymphoid enhancer binding factor 1.
    
 0.712
TLE4
TLE family member 4, transcriptional corepressor.
  
 
0.705
NKX2-2
NK2 homeobox 2.
    
 
 0.660
CTNNB1
Catenin beta 1.
    
 0.626
PITPNB
Phosphatidylinositol transfer protein beta.
      
 0.617
NSG1
Neuronal vesicle trafficking associated 1.
      
 0.617
ETNK1
Ethanolamine kinase 1.
      
 0.612
ENSCSAP00000016053
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.596
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.