Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
SRCTyrosine-protein kinase. (633 aa)    
Predicted Functional Partners:
FYN
Tyrosine-protein kinase.
  
0.999
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.998
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.998
SHC1
SHC adaptor protein 1.
   
0.998
ESR1
Estrogen receptor 1.
    
 0.997
STAT3
Signal transducer and activator of transcription.
   
 0.997
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.997
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.996
EGFR
Receptor protein-tyrosine kinase.
    
0.996
ERBB2
Receptor protein-tyrosine kinase.
    
0.995
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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