Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KLHL12BTB domain-containing protein. (527 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.993
RBX1
Ring-box 1.
    
 0.951
FBXL17
F-box and leucine rich repeat protein 17.
    
 0.944
SEC31A
SEC31 homolog A, COPII coat complex component.
    
 0.927
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.890
SEC31B
SEC31 homolog B, COPII coat complex component.
    
 0.880
PDCD6
Programmed cell death 6.
    
 0.877
PEF1
Penta-EF-hand domain containing 1.
    
 0.877
DVL3
Dishevelled segment polarity protein 3.
    
 0.856
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
 0.849
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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