Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)    
Predicted Functional Partners:
INHBA
Inhibin subunit beta A.
   
 0.991
BMP2
Bone morphogenetic protein 2.
    
 0.989
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
  
0.988
MSTN
Myostatin.
   
 0.987
ACVR2A
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
  
 
0.987
BMP6
Bone morphogenetic protein 6.
    
 0.986
INHBB
Inhibin subunit beta B.
   
 0.983
BMP4
Bone morphogenetic protein 4.
    
 0.982
GDF11
Growth differentiation factor 11.
   
 0.981
SMAD2
Mothers against decapentaplegic homolog.
   
 0.981
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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