Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIM1SIM bHLH transcription factor 1. (766 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
    
 
0.854
FOXG1
Forkhead box G1.
    
 
 0.721
KIAA0408
KIAA0408.
      
 0.673
KCNC4
Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family.
      
 0.673
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
    
 
 0.658
OTP
Orthopedia homeobox.
   
 
 0.591
MC4R
Melanocortin 4 receptor.
      
 0.572
SIL1
SIL1 nucleotide exchange factor.
      
 0.558
TSPO2
Translocator protein 2.
      
 0.546
UGT2A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.544
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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