Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MEF2CMyocyte enhancer factor 2C. (446 aa)    
Predicted Functional Partners:
MEF2A
Myocyte enhancer factor 2A.
  
0.997
MEF2D
Myocyte enhancer factor 2D.
   
0.986
MAPK11
Mitogen-activated protein kinase.
    
 0.972
MAPK14
Mitogen-activated protein kinase.
    
 0.970
MAPK12
Mitogen-activated protein kinase.
    
 0.968
MAPK13
Mitogen-activated protein kinase.
    
 0.964
HDAC4
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 
 0.945
NKX2-5
NK2 homeobox 5.
    
 0.939
NFATC1
Nuclear factor of activated T cells 1.
   
 0.919
NFATC2
Nuclear factor of activated T cells 2.
   
 0.914
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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