STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD40CD40 molecule. (278 aa)    
Predicted Functional Partners:
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 0.999
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.976
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.971
TRAF2
TNF receptor-associated factor.
   
 0.970
CD86
CD86 molecule.
   
  
 0.926
CD80
Ig-like domain-containing protein.
   
 
 0.917
CD4
CD4 molecule.
   
  
 0.897
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
  
 0.859
CD83
CD83 molecule.
   
  
 0.855
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.824
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.