| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALS2 | SETX | ENSCSAP00000006791 | ENSCSAP00000011024 | VPS9 domain-containing protein. | Senataxin. | 0.782 |
| BRCA1 | POLR2A | ENSCSAP00000014651 | ENSCSAP00000007724 | Uncharacterized protein. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.930 |
| BRCA1 | SETX | ENSCSAP00000014651 | ENSCSAP00000011024 | Uncharacterized protein. | Senataxin. | 0.867 |
| DROSHA | RNASEH1 | ENSCSAP00000013240 | ENSCSAP00000003230 | Drosha ribonuclease III. | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.436 |
| DROSHA | SCAF4 | ENSCSAP00000013240 | ENSCSAP00000005686 | Drosha ribonuclease III. | SR-related CTD associated factor 4. | 0.644 |
| DROSHA | SCAF8 | ENSCSAP00000013240 | ENSCSAP00000009584 | Drosha ribonuclease III. | SR-related CTD associated factor 8. | 0.652 |
| DROSHA | SETX | ENSCSAP00000013240 | ENSCSAP00000011024 | Drosha ribonuclease III. | Senataxin. | 0.747 |
| DROSHA | XRN2 | ENSCSAP00000013240 | ENSCSAP00000007303 | Drosha ribonuclease III. | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. | 0.520 |
| NIPBL | SETX | ENSCSAP00000013055 | ENSCSAP00000011024 | Nipped-B protein. | Senataxin. | 0.779 |
| POLR2A | BRCA1 | ENSCSAP00000007724 | ENSCSAP00000014651 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Uncharacterized protein. | 0.930 |
| POLR2A | SCAF4 | ENSCSAP00000007724 | ENSCSAP00000005686 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | SR-related CTD associated factor 4. | 0.756 |
| POLR2A | SCAF8 | ENSCSAP00000007724 | ENSCSAP00000009584 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | SR-related CTD associated factor 8. | 0.756 |
| POLR2A | SETX | ENSCSAP00000007724 | ENSCSAP00000011024 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Senataxin. | 0.863 |
| POLR2A | SUPT5H | ENSCSAP00000007724 | ENSCSAP00000000189 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcription elongation factor SPT5. | 0.987 |
| POLR2A | XRN2 | ENSCSAP00000007724 | ENSCSAP00000007303 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. | 0.819 |
| RNASEH1 | DROSHA | ENSCSAP00000003230 | ENSCSAP00000013240 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Drosha ribonuclease III. | 0.436 |
| RNASEH1 | SETX | ENSCSAP00000003230 | ENSCSAP00000011024 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Senataxin. | 0.826 |
| SCAF4 | DROSHA | ENSCSAP00000005686 | ENSCSAP00000013240 | SR-related CTD associated factor 4. | Drosha ribonuclease III. | 0.644 |
| SCAF4 | POLR2A | ENSCSAP00000005686 | ENSCSAP00000007724 | SR-related CTD associated factor 4. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.756 |
| SCAF4 | SCAF8 | ENSCSAP00000005686 | ENSCSAP00000009584 | SR-related CTD associated factor 4. | SR-related CTD associated factor 8. | 0.923 |
