Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)    
Predicted Functional Partners:
GSR
Glutathione-disulfide reductase.
  
 0.987
GPX4
Uncharacterized protein.
   
 
 0.974
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
0.958
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.955
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 
0.949
PRDX6
Peroxiredoxin 6.
   
 0.945
PPARGC1A
PPARG coactivator 1 alpha.
     
 0.943
GSS
Glutathione synthetase.
     
 0.916
GGT6
Gamma-glutamyltransferase 6.
     
 0.913
GPX5
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
  
0.911
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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