STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1605 aa)    
Predicted Functional Partners:
DVL1
Dishevelled segment polarity protein 1.
    
 0.763
UBC
Uncharacterized protein.
    
 0.755
RHOBTB3
Rho related BTB domain containing 3.
    
 0.679
SMAD4
Mothers against decapentaplegic homolog.
   
 0.642
ZMAT4
Zinc finger matrin-type 4.
   
 
 0.639
ANKRD6
Ankyrin repeat domain 6.
    
 0.637
LANCL2
LanC like 2.
    
 
 0.634
URGCP
Upregulator of cell proliferation.
    
 
 0.628
CCDC117
Coiled-coil domain containing 117.
      
 0.625
VOPP1
VOPP1 WW domain binding protein.
    
 
 0.624
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.