Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VAV2Vav guanine nucleotide exchange factor 2. (896 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase.
   
 0.995
CDC42
Cell division cycle 42.
   
 0.988
LCP2
Lymphocyte cytosolic protein 2.
   
 0.987
RHOA
Ras homolog family member A.
    
 0.977
RAC3
Rac family small GTPase 3.
   
 0.974
RAC2
Rac family small GTPase 2.
   
 0.972
ZAP70
Tyrosine-protein kinase.
   
 0.972
RAC1
Rac family small GTPase 1.
   
 0.972
ENSCSAP00000002624
Uncharacterized protein.
   
 0.971
ENSCSAP00000002631
Ig-like domain-containing protein.
   
 0.971
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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