STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)    
Predicted Functional Partners:
TGFBR2
TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]
   
 0.955
LTBP3
Latent transforming growth factor beta binding protein 3.
   
 0.839
LTBP1
Latent transforming growth factor beta binding protein 1.
   
 0.837
LTBP2
Latent transforming growth factor beta binding protein 2.
   
 0.734
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.721
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
0.701
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.687
TGFB3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 
0.685
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.673
SMAD3
Mothers against decapentaplegic homolog.
   
 0.668
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.