| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK9 | CMPK1 | ENSCSAP00000011452 | ENSCSAP00000016765 | Adenylate kinase 9. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.961 |
| AK9 | CMPK2 | ENSCSAP00000011452 | ENSCSAP00000003310 | Adenylate kinase 9. | Cytidine/uridine monophosphate kinase 2. | 0.957 |
| AK9 | CTPS1 | ENSCSAP00000011452 | ENSCSAP00000016860 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.943 |
| AK9 | CTPS2 | ENSCSAP00000011452 | ENSCSAP00000010935 | Adenylate kinase 9. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.943 |
| AK9 | DTYMK | ENSCSAP00000011452 | ENSCSAP00000002062 | Adenylate kinase 9. | Deoxythymidylate kinase. | 0.957 |
| AK9 | DUT | ENSCSAP00000011452 | ENSCSAP00000006714 | Adenylate kinase 9. | Deoxyuridine triphosphatase. | 0.949 |
| AK9 | ITPA | ENSCSAP00000011452 | ENSCSAP00000009450 | Adenylate kinase 9. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.933 |
| AK9 | NME4 | ENSCSAP00000011452 | ENSCSAP00000008974 | Adenylate kinase 9. | Nucleoside diphosphate kinase. | 0.955 |
| AK9 | NME6 | ENSCSAP00000011452 | ENSCSAP00000011981 | Adenylate kinase 9. | Nucleoside diphosphate kinase. | 0.955 |
| AK9 | RRM1 | ENSCSAP00000011452 | ENSCSAP00000000608 | Adenylate kinase 9. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.980 |
| CMPK1 | AK9 | ENSCSAP00000016765 | ENSCSAP00000011452 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Adenylate kinase 9. | 0.961 |
| CMPK1 | CMPK2 | ENSCSAP00000016765 | ENSCSAP00000003310 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Cytidine/uridine monophosphate kinase 2. | 0.974 |
| CMPK1 | CTPS1 | ENSCSAP00000016765 | ENSCSAP00000016860 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.512 |
| CMPK1 | CTPS2 | ENSCSAP00000016765 | ENSCSAP00000010935 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.512 |
| CMPK1 | DTYMK | ENSCSAP00000016765 | ENSCSAP00000002062 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Deoxythymidylate kinase. | 0.756 |
| CMPK1 | DUT | ENSCSAP00000016765 | ENSCSAP00000006714 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Deoxyuridine triphosphatase. | 0.935 |
| CMPK1 | NME4 | ENSCSAP00000016765 | ENSCSAP00000008974 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase. | 0.964 |
| CMPK1 | NME6 | ENSCSAP00000016765 | ENSCSAP00000011981 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase. | 0.942 |
| CMPK1 | RRM1 | ENSCSAP00000016765 | ENSCSAP00000000608 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.955 |
| CMPK2 | AK9 | ENSCSAP00000003310 | ENSCSAP00000011452 | Cytidine/uridine monophosphate kinase 2. | Adenylate kinase 9. | 0.957 |
