node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARPC1B | EFS | ENSCSAP00000013808 | ENSCSAP00000012092 | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. | Embryonal Fyn-associated substrate. | 0.570 |
ARPC1B | ITSN2 | ENSCSAP00000013808 | ENSCSAP00000004709 | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. | Intersectin 2. | 0.922 |
CRK | CRKL | ENSCSAP00000010203 | ENSCSAP00000009368 | CRK proto-oncogene, adaptor protein. | CRK like proto-oncogene, adaptor protein. | 0.961 |
CRK | EFS | ENSCSAP00000010203 | ENSCSAP00000012092 | CRK proto-oncogene, adaptor protein. | Embryonal Fyn-associated substrate. | 0.626 |
CRK | LPXN | ENSCSAP00000010203 | ENSCSAP00000002321 | CRK proto-oncogene, adaptor protein. | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). | 0.769 |
CRK | PTK2 | ENSCSAP00000010203 | ENSCSAP00000005821 | CRK proto-oncogene, adaptor protein. | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.818 |
CRK | PTK2B | ENSCSAP00000010203 | ENSCSAP00000012076 | CRK proto-oncogene, adaptor protein. | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.962 |
CRK | PXN | ENSCSAP00000010203 | ENSCSAP00000015767 | CRK proto-oncogene, adaptor protein. | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. | 0.976 |
CRK | RAPGEF1 | ENSCSAP00000010203 | ENSCSAP00000010997 | CRK proto-oncogene, adaptor protein. | Rap guanine nucleotide exchange factor 1. | 0.994 |
CRKL | CRK | ENSCSAP00000009368 | ENSCSAP00000010203 | CRK like proto-oncogene, adaptor protein. | CRK proto-oncogene, adaptor protein. | 0.961 |
CRKL | EFS | ENSCSAP00000009368 | ENSCSAP00000012092 | CRK like proto-oncogene, adaptor protein. | Embryonal Fyn-associated substrate. | 0.626 |
CRKL | LPXN | ENSCSAP00000009368 | ENSCSAP00000002321 | CRK like proto-oncogene, adaptor protein. | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). | 0.695 |
CRKL | PTK2 | ENSCSAP00000009368 | ENSCSAP00000005821 | CRK like proto-oncogene, adaptor protein. | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.567 |
CRKL | PTK2B | ENSCSAP00000009368 | ENSCSAP00000012076 | CRK like proto-oncogene, adaptor protein. | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.954 |
CRKL | PXN | ENSCSAP00000009368 | ENSCSAP00000015767 | CRK like proto-oncogene, adaptor protein. | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. | 0.978 |
CRKL | RAPGEF1 | ENSCSAP00000009368 | ENSCSAP00000010997 | CRK like proto-oncogene, adaptor protein. | Rap guanine nucleotide exchange factor 1. | 0.997 |
EFS | ARPC1B | ENSCSAP00000012092 | ENSCSAP00000013808 | Embryonal Fyn-associated substrate. | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. | 0.570 |
EFS | CRK | ENSCSAP00000012092 | ENSCSAP00000010203 | Embryonal Fyn-associated substrate. | CRK proto-oncogene, adaptor protein. | 0.626 |
EFS | CRKL | ENSCSAP00000012092 | ENSCSAP00000009368 | Embryonal Fyn-associated substrate. | CRK like proto-oncogene, adaptor protein. | 0.626 |
EFS | ITSN2 | ENSCSAP00000012092 | ENSCSAP00000004709 | Embryonal Fyn-associated substrate. | Intersectin 2. | 0.857 |