STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EN1Homeobox protein engrailed-like. (395 aa)    
Predicted Functional Partners:
FOXA2
Forkhead box A2.
    
 
 0.785
PAX2
Paired box 2.
   
  
 0.761
SPRY1
Sprouty RTK signaling antagonist 1.
      
 0.753
PAX8
Paired box 8.
   
  
 0.743
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.721
ETV5
ETS variant 5.
      
 0.647
FOXG1
Forkhead box G1.
   
  
 0.621
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.620
CNPY1
Canopy FGF signaling regulator 1.
   
  
 0.605
OTX2
Orthodenticle homeobox 2.
   
  
 0.575
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.