Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISL1ISL LIM homeobox 1. (349 aa)    
Predicted Functional Partners:
LDB1
LIM domain binding 1.
    
 0.968
LHX4
LIM homeobox 4.
   
 0.968
SSBP2
Single stranded DNA binding protein 2.
    
 
 0.920
SSBP4
Single stranded DNA binding protein 4.
    
 
 0.912
LHX3
LIM homeobox 3.
   
 0.889
GATA4
GATA binding protein 4.
    
 0.801
NKX2-5
NK2 homeobox 5.
    
 0.796
GABRP
Gamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.793
ENSCSAP00000012541
Uncharacterized protein.
    
 0.790
TBX20
T-box transcription factor 20.
   
 0.779
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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