STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRK1Leucine rich repeat kinase 1. (2015 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.826
SHC1
SHC adaptor protein 1.
    
  0.769
BAG5
BCL2 associated athanogene 5.
    
   0.757
ABL1
Tyrosine-protein kinase.
   
  0.745
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
 0.641
GSK3A
Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily.
    
 0.615
RTL4
Retrotransposon Gag like 4.
    
 0.595
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 
 0.588
EGFR
Receptor protein-tyrosine kinase.
    
 0.584
SHC3
SHC adaptor protein 3.
    
 0.557
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.