Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTNNB1Catenin beta 1. (781 aa)    
Predicted Functional Partners:
LEF1
Lymphoid enhancer binding factor 1.
    
 0.999
CDH1
Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.999
ENSCSAP00000001444
HMG box domain-containing protein.
    
 0.999
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.999
AXIN1
Axin 1.
    
 0.999
AXIN2
Axin 2.
    
 0.998
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.998
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
   
 0.998
CTNNA1
Catenin alpha 1.
   
 0.998
APC
APC regulator of WNT signaling pathway.
   
 0.998
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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