node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSG1 | IL1RL2 | ENSCSAP00000013859 | ENSCSAP00000013164 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | Interleukin 1 receptor like 2. | 0.908 |
IL1B | IL1RAP | ENSCSAP00000012813 | ENSCSAP00000005242 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 1 receptor accessory protein. | 0.968 |
IL1B | IL1RL2 | ENSCSAP00000012813 | ENSCSAP00000013164 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 1 receptor like 2. | 0.861 |
IL1B | IL1RN | ENSCSAP00000012813 | ENSCSAP00000012751 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.656 |
IL1B | IL33 | ENSCSAP00000012813 | ENSCSAP00000005178 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 33. | 0.631 |
IL1B | IL36A | ENSCSAP00000012813 | ENSCSAP00000012794 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.417 |
IL1B | IL36G | ENSCSAP00000012813 | ENSCSAP00000012801 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.528 |
IL1B | IL36RN | ENSCSAP00000012813 | ENSCSAP00000012780 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.423 |
IL1F10 | IL1RAP | ENSCSAP00000012773 | ENSCSAP00000005242 | Interleukin 1 family member 10. | Interleukin 1 receptor accessory protein. | 0.692 |
IL1F10 | IL1RL2 | ENSCSAP00000012773 | ENSCSAP00000013164 | Interleukin 1 family member 10. | Interleukin 1 receptor like 2. | 0.985 |
IL1F10 | IL36A | ENSCSAP00000012773 | ENSCSAP00000012794 | Interleukin 1 family member 10. | Interleukin-1. | 0.443 |
IL1F10 | IL36B | ENSCSAP00000012773 | ENSCSAP00000012784 | Interleukin 1 family member 10. | Interleukin-1. | 0.553 |
IL1F10 | IL36G | ENSCSAP00000012773 | ENSCSAP00000012801 | Interleukin 1 family member 10. | Interleukin-1. | 0.431 |
IL1F10 | IL36RN | ENSCSAP00000012773 | ENSCSAP00000012780 | Interleukin 1 family member 10. | Interleukin-1. | 0.417 |
IL1RAP | IL1B | ENSCSAP00000005242 | ENSCSAP00000012813 | Interleukin 1 receptor accessory protein. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.968 |
IL1RAP | IL1F10 | ENSCSAP00000005242 | ENSCSAP00000012773 | Interleukin 1 receptor accessory protein. | Interleukin 1 family member 10. | 0.692 |
IL1RAP | IL1RL2 | ENSCSAP00000005242 | ENSCSAP00000013164 | Interleukin 1 receptor accessory protein. | Interleukin 1 receptor like 2. | 0.924 |
IL1RAP | IL1RN | ENSCSAP00000005242 | ENSCSAP00000012751 | Interleukin 1 receptor accessory protein. | Interleukin-1. | 0.553 |
IL1RAP | IL33 | ENSCSAP00000005242 | ENSCSAP00000005178 | Interleukin 1 receptor accessory protein. | Interleukin 33. | 0.937 |
IL1RAP | IL36A | ENSCSAP00000005242 | ENSCSAP00000012794 | Interleukin 1 receptor accessory protein. | Interleukin-1. | 0.716 |