STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBX18T-box transcription factor 18. (607 aa)    
Predicted Functional Partners:
SHOX2
Short stature homeobox 2.
   
 
 0.691
NKX2-5
NK2 homeobox 5.
    
 
 0.653
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
      
 0.639
WT1
WT1 transcription factor.
      
 0.618
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.614
CACNA1H
Calcium voltage-gated channel subunit alpha1 H.
      
 0.579
IRX4
Iroquois homeobox 4.
    
 
 0.524
LHFPL4
LHFPL tetraspan subfamily member 4.
    
 
 0.504
ISL1
ISL LIM homeobox 1.
    
 
 0.458
HOXC4
Homeobox C4.
   
 
 0.436
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.