BIRC8 protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BIRC8

RING-type domain-containing protein. (236 aa)

Predicted Functional Partners:

DIABLO

0.955

CASP3

0.948

CASP9

0.935

ENSCSAP00000002083

0.934

CASP7

0.928

TAB1

0.909

SEPTIN4

0.891

BIRC7

0.865

BIRC3

0.864

APAF1

0.854

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BIRC3	ENSCSAP00000014527	ENSCSAP00000014823	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 3.	0.703
APAF1	BIRC7	ENSCSAP00000014527	ENSCSAP00000012340	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 7.	0.673
APAF1	BIRC8	ENSCSAP00000014527	ENSCSAP00000013451	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	RING-type domain-containing protein.	0.854
APAF1	CASP3	ENSCSAP00000014527	ENSCSAP00000015040	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 3; Belongs to the peptidase C14A family.	0.997
APAF1	CASP7	ENSCSAP00000014527	ENSCSAP00000001418	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 7; Belongs to the peptidase C14A family.	0.858
APAF1	CASP9	ENSCSAP00000014527	ENSCSAP00000017173	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	DIABLO	ENSCSAP00000014527	ENSCSAP00000015891	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.759
BIRC3	APAF1	ENSCSAP00000014823	ENSCSAP00000014527	Baculoviral IAP repeat containing 3.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.703
BIRC3	BIRC7	ENSCSAP00000014823	ENSCSAP00000012340	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat containing 7.	0.766
BIRC3	BIRC8	ENSCSAP00000014823	ENSCSAP00000013451	Baculoviral IAP repeat containing 3.	RING-type domain-containing protein.	0.864
BIRC3	CASP3	ENSCSAP00000014823	ENSCSAP00000015040	Baculoviral IAP repeat containing 3.	Caspase 3; Belongs to the peptidase C14A family.	0.994
BIRC3	CASP7	ENSCSAP00000014823	ENSCSAP00000001418	Baculoviral IAP repeat containing 3.	Caspase 7; Belongs to the peptidase C14A family.	0.988
BIRC3	CASP9	ENSCSAP00000014823	ENSCSAP00000017173	Baculoviral IAP repeat containing 3.	Caspase 9; Belongs to the peptidase C14A family.	0.989
BIRC3	DIABLO	ENSCSAP00000014823	ENSCSAP00000015891	Baculoviral IAP repeat containing 3.	Uncharacterized protein.	0.988
BIRC3	ENSCSAP00000002083	ENSCSAP00000014823	ENSCSAP00000002083	Baculoviral IAP repeat containing 3.	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.432
BIRC3	SEPTIN4	ENSCSAP00000014823	ENSCSAP00000002086	Baculoviral IAP repeat containing 3.	Septin 4.	0.941
BIRC3	TAB1	ENSCSAP00000014823	ENSCSAP00000002648	Baculoviral IAP repeat containing 3.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.969
BIRC7	APAF1	ENSCSAP00000012340	ENSCSAP00000014527	Baculoviral IAP repeat containing 7.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.673
BIRC7	BIRC3	ENSCSAP00000012340	ENSCSAP00000014823	Baculoviral IAP repeat containing 7.	Baculoviral IAP repeat containing 3.	0.766
BIRC7	BIRC8	ENSCSAP00000012340	ENSCSAP00000013451	Baculoviral IAP repeat containing 7.	RING-type domain-containing protein.	0.865

page 1 of 4

Server load: low (34%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About