Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.999
CUL4B
Cullin 4B; Belongs to the cullin family.
  
0.999
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.997
RBX1
Ring-box 1.
    
 0.995
DDB2
Damage specific DNA binding protein 2.
    
 0.990
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.988
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.987
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.985
CRBN
Cereblon.
    
 0.981
ENSCSAP00000018574
Ubiquitin-like domain-containing protein.
    
 0.980
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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