| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCM2 | RHOA | ENSCSAP00000011794 | ENSCSAP00000011176 | CCM2 scaffold protein. | Ras homolog family member A. | 0.534 |
| CCM2 | SMURF1 | ENSCSAP00000011794 | ENSCSAP00000013793 | CCM2 scaffold protein. | E3 ubiquitin-protein ligase. | 0.970 |
| CCM2 | SMURF2 | ENSCSAP00000011794 | ENSCSAP00000000389 | CCM2 scaffold protein. | SMAD specific E3 ubiquitin protein ligase 2. | 0.947 |
| PTCH1 | PTCH2 | ENSCSAP00000002732 | ENSCSAP00000016807 | Patched 1. | Patched 2. | 0.910 |
| PTCH1 | SMURF1 | ENSCSAP00000002732 | ENSCSAP00000013793 | Patched 1. | E3 ubiquitin-protein ligase. | 0.984 |
| PTCH1 | SMURF2 | ENSCSAP00000002732 | ENSCSAP00000000389 | Patched 1. | SMAD specific E3 ubiquitin protein ligase 2. | 0.984 |
| PTCH2 | PTCH1 | ENSCSAP00000016807 | ENSCSAP00000002732 | Patched 2. | Patched 1. | 0.910 |
| PTCH2 | SMURF1 | ENSCSAP00000016807 | ENSCSAP00000013793 | Patched 2. | E3 ubiquitin-protein ligase. | 0.966 |
| PTCH2 | SMURF2 | ENSCSAP00000016807 | ENSCSAP00000000389 | Patched 2. | SMAD specific E3 ubiquitin protein ligase 2. | 0.966 |
| RHOA | CCM2 | ENSCSAP00000011176 | ENSCSAP00000011794 | Ras homolog family member A. | CCM2 scaffold protein. | 0.534 |
| RHOA | SMURF1 | ENSCSAP00000011176 | ENSCSAP00000013793 | Ras homolog family member A. | E3 ubiquitin-protein ligase. | 0.996 |
| RHOA | SMURF2 | ENSCSAP00000011176 | ENSCSAP00000000389 | Ras homolog family member A. | SMAD specific E3 ubiquitin protein ligase 2. | 0.985 |
| RHOA | TGFBR1 | ENSCSAP00000011176 | ENSCSAP00000007285 | Ras homolog family member A. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.657 |
| RHOA | TGFBR2 | ENSCSAP00000011176 | ENSCSAP00000005897 | Ras homolog family member A. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.954 |
| SMAD5 | SMAD6 | ENSCSAP00000009511 | ENSCSAP00000009415 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.971 |
| SMAD5 | SMAD7 | ENSCSAP00000009511 | ENSCSAP00000014041 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.968 |
| SMAD5 | SMURF1 | ENSCSAP00000009511 | ENSCSAP00000013793 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.967 |
| SMAD5 | SMURF2 | ENSCSAP00000009511 | ENSCSAP00000000389 | Mothers against decapentaplegic homolog. | SMAD specific E3 ubiquitin protein ligase 2. | 0.886 |
| SMAD5 | TGFBR1 | ENSCSAP00000009511 | ENSCSAP00000007285 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.673 |
| SMAD5 | TGFBR2 | ENSCSAP00000009511 | ENSCSAP00000005897 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.592 |
