Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
KPNA7Importin subunit alpha; Functions in nuclear protein import. (493 aa)    
Predicted Functional Partners:
KPNB1
Karyopherin subunit beta 1.
   
 0.915
CDK1
Protein kinase domain-containing protein.
   
 0.796
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
     
  0.783
NUP50
Nucleoporin 50.
   
 
 0.765
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.746
DLGAP5
DLG associated protein 5.
   
  
 0.717
PBK
PDZ binding kinase.
   
 0.717
NUP153
Nucleoporin 153.
   
 
 0.706
CSE1L
Chromosome segregation 1 like.
   
 
 0.687
CNTD2
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.670
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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