STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)    
Predicted Functional Partners:
BCL2L11
BCL2 like 11.
    
 0.989
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1.
    
 0.978
BBC3
Uncharacterized protein.
   
 0.950
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.946
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 
 0.936
BAK1
BCL2 antagonist/killer 1.
    
0.935
GZMB
Granzyme B; Belongs to the peptidase S1 family.
   
 
 0.905
TNKS2
Poly [ADP-ribose] polymerase.
    
 
 0.841
HRK
Activator of apoptosis harakiri; Promotes apoptosis.
    
 
 0.810
BMF
Bcl2 modifying factor.
    
 0.806
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.