| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCSAP00000004852 | LOC103221971 | ENSCSAP00000004852 | ENSCSAP00000018748 | Uncharacterized protein. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.953 |
| ENSCSAP00000004852 | MPHOSPH8 | ENSCSAP00000004852 | ENSCSAP00000014111 | Uncharacterized protein. | M-phase phosphoprotein 8. | 0.832 |
| ENSCSAP00000004852 | SETDB1 | ENSCSAP00000004852 | ENSCSAP00000014051 | Uncharacterized protein. | SET domain bifurcated histone lysine methyltransferase 1. | 0.564 |
| LOC103221971 | ENSCSAP00000004852 | ENSCSAP00000018748 | ENSCSAP00000004852 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein. | 0.953 |
| LOC103221971 | MAPRE1 | ENSCSAP00000018748 | ENSCSAP00000008713 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Microtubule associated protein RP/EB family member 1. | 0.460 |
| LOC103221971 | MAPRE2 | ENSCSAP00000018748 | ENSCSAP00000013919 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Microtubule associated protein RP/EB family member 2. | 0.460 |
| LOC103221971 | MAPRE3 | ENSCSAP00000018748 | ENSCSAP00000005669 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Microtubule associated protein RP/EB family member 3. | 0.460 |
| LOC103221971 | MPHOSPH8 | ENSCSAP00000018748 | ENSCSAP00000014111 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | M-phase phosphoprotein 8. | 0.808 |
| LOC103221971 | SETDB1 | ENSCSAP00000018748 | ENSCSAP00000014051 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | SET domain bifurcated histone lysine methyltransferase 1. | 0.638 |
| LOC103221971 | SIRT1 | ENSCSAP00000018748 | ENSCSAP00000003766 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Sirtuin 1. | 0.908 |
| LOC103221971 | SIRT5 | ENSCSAP00000018748 | ENSCSAP00000003795 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.765 |
| LOC103221971 | TASOR | ENSCSAP00000018748 | ENSCSAP00000009004 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Transcription activation suppressor. | 0.712 |
| MAPRE1 | LOC103221971 | ENSCSAP00000008713 | ENSCSAP00000018748 | Microtubule associated protein RP/EB family member 1. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.460 |
| MAPRE1 | MAPRE2 | ENSCSAP00000008713 | ENSCSAP00000013919 | Microtubule associated protein RP/EB family member 1. | Microtubule associated protein RP/EB family member 2. | 0.909 |
| MAPRE1 | MAPRE3 | ENSCSAP00000008713 | ENSCSAP00000005669 | Microtubule associated protein RP/EB family member 1. | Microtubule associated protein RP/EB family member 3. | 0.909 |
| MAPRE1 | MPHOSPH8 | ENSCSAP00000008713 | ENSCSAP00000014111 | Microtubule associated protein RP/EB family member 1. | M-phase phosphoprotein 8. | 0.796 |
| MAPRE2 | LOC103221971 | ENSCSAP00000013919 | ENSCSAP00000018748 | Microtubule associated protein RP/EB family member 2. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.460 |
| MAPRE2 | MAPRE1 | ENSCSAP00000013919 | ENSCSAP00000008713 | Microtubule associated protein RP/EB family member 2. | Microtubule associated protein RP/EB family member 1. | 0.909 |
| MAPRE2 | MAPRE3 | ENSCSAP00000013919 | ENSCSAP00000005669 | Microtubule associated protein RP/EB family member 2. | Microtubule associated protein RP/EB family member 3. | 0.915 |
| MAPRE2 | MPHOSPH8 | ENSCSAP00000013919 | ENSCSAP00000014111 | Microtubule associated protein RP/EB family member 2. | M-phase phosphoprotein 8. | 0.796 |
