Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)    
Predicted Functional Partners:
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.999
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
0.989
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
0.987
TNIP2
TNFAIP3 interacting protein 2.
   
 0.987
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
  
0.967
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
0.964
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
    
0.958
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.955
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.951
AKT2
Non-specific serine/threonine protein kinase.
   
 
0.944
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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