Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GAB1GRB2 associated binding protein 1. (751 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.999
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.998
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.996
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
   
 0.996
EGFR
Receptor protein-tyrosine kinase.
   
 0.996
CRK
CRK proto-oncogene, adaptor protein.
    
 0.994
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.990
SHC1
SHC adaptor protein 1.
    
 0.990
SHC3
SHC adaptor protein 3.
    
 0.982
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.979
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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