STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (591 aa)    
Predicted Functional Partners:
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2.
   
 
 0.913
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
    
 
 0.828
PRDM14
PR/SET domain 14.
   
 
 0.817
RUNX1T1
RUNX1 partner transcriptional co-repressor 1.
    
   0.791
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 
 0.781
TCF12
Transcription factor 12.
   
 
 0.771
PRDM6
PR/SET domain 6.
    
 
 0.760
NCOR1
Nuclear receptor corepressor 1.
   
 0.694
TCF4
Transcription factor 4.
   
 
 0.693
LDB1
LIM domain binding 1.
    
 
 0.681
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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