STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (591 aa)    
Predicted Functional Partners:
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
    
 0.731
LDB1
LIM domain binding 1.
    
 
 0.670
DHX38
DEAH-box helicase 38.
   
 
 0.659
ZNF652
Zinc finger protein 652.
   
 0.658
ENSCSAP00000012541
Uncharacterized protein.
    
 
 0.641
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
    
 
 0.636
HIVEP2
Human immunodeficiency virus type I enhancer binding protein 2.
   
 0.631
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
      
 0.631
BHLHE40
Basic helix-loop-helix family member e40.
    
 
 0.621
LMO2
LIM domain only 2.
    
 
 0.596
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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