| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCNA1 | CCNA2 | ENSCSAP00000013896 | ENSCSAP00000000070 | Cyclin A1; Belongs to the cyclin family. | Cyclin A2; Belongs to the cyclin family. | 0.994 |
| CCNA1 | CDC6 | ENSCSAP00000013896 | ENSCSAP00000015262 | Cyclin A1; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.996 |
| CCNA1 | CDK2 | ENSCSAP00000013896 | ENSCSAP00000001593 | Cyclin A1; Belongs to the cyclin family. | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA1 | CDT1 | ENSCSAP00000013896 | ENSCSAP00000015142 | Cyclin A1; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.964 |
| CCNA1 | MCM10 | ENSCSAP00000013896 | ENSCSAP00000009346 | Cyclin A1; Belongs to the cyclin family. | Minichromosome maintenance 10 replication initiation factor. | 0.729 |
| CCNA1 | MCM3 | ENSCSAP00000013896 | ENSCSAP00000009229 | Cyclin A1; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.813 |
| CCNA1 | MCM7 | ENSCSAP00000013896 | ENSCSAP00000013867 | Cyclin A1; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.828 |
| CCNA1 | ORC1 | ENSCSAP00000013896 | ENSCSAP00000016740 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.912 |
| CCNA1 | ORC3 | ENSCSAP00000013896 | ENSCSAP00000013377 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 3. | 0.688 |
| CCNA1 | ORC6 | ENSCSAP00000013896 | ENSCSAP00000001868 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 6. | 0.698 |
| CCNA2 | CCNA1 | ENSCSAP00000000070 | ENSCSAP00000013896 | Cyclin A2; Belongs to the cyclin family. | Cyclin A1; Belongs to the cyclin family. | 0.994 |
| CCNA2 | CDC6 | ENSCSAP00000000070 | ENSCSAP00000015262 | Cyclin A2; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
| CCNA2 | CDK2 | ENSCSAP00000000070 | ENSCSAP00000001593 | Cyclin A2; Belongs to the cyclin family. | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA2 | CDT1 | ENSCSAP00000000070 | ENSCSAP00000015142 | Cyclin A2; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.985 |
| CCNA2 | MCM10 | ENSCSAP00000000070 | ENSCSAP00000009346 | Cyclin A2; Belongs to the cyclin family. | Minichromosome maintenance 10 replication initiation factor. | 0.746 |
| CCNA2 | MCM3 | ENSCSAP00000000070 | ENSCSAP00000009229 | Cyclin A2; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.810 |
| CCNA2 | MCM7 | ENSCSAP00000000070 | ENSCSAP00000013867 | Cyclin A2; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.835 |
| CCNA2 | ORC1 | ENSCSAP00000000070 | ENSCSAP00000016740 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.959 |
| CCNA2 | ORC3 | ENSCSAP00000000070 | ENSCSAP00000013377 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 3. | 0.635 |
| CCNA2 | ORC6 | ENSCSAP00000000070 | ENSCSAP00000001868 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 6. | 0.677 |
