Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBLCbl proto-oncogene. (907 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
    
 0.999
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.997
GRB2
Growth factor receptor bound protein 2.
    
 0.995
VAV1
Vav guanine nucleotide exchange factor 1.
    
 0.995
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.994
CRK
CRK proto-oncogene, adaptor protein.
    
 0.994
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.994
SPRY2
Sprouty RTK signaling antagonist 2.
    
 0.993
ABL1
Tyrosine-protein kinase.
   
 0.992
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.985
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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