| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDNF | FRS2 | ENSCSAP00000018826 | ENSCSAP00000000568 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Fibroblast growth factor receptor substrate 2. | 0.859 |
| BDNF | GRB2 | ENSCSAP00000018826 | ENSCSAP00000001067 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Growth factor receptor bound protein 2. | 0.564 |
| BDNF | NGF | ENSCSAP00000018826 | ENSCSAP00000017821 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Nerve growth factor; Belongs to the NGF-beta family. | 0.880 |
| BDNF | NTF3 | ENSCSAP00000018826 | ENSCSAP00000007186 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.693 |
| BDNF | NTF4 | ENSCSAP00000018826 | ENSCSAP00000019140 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Neurotrophin 4; Belongs to the NGF-beta family. | 0.954 |
| BDNF | NTRK1 | ENSCSAP00000018826 | ENSCSAP00000015828 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Tyrosine-protein kinase receptor. | 0.970 |
| BDNF | PIK3CA | ENSCSAP00000018826 | ENSCSAP00000009123 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.791 |
| BDNF | PLCG1 | ENSCSAP00000018826 | ENSCSAP00000010095 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Phosphoinositide phospholipase C. | 0.615 |
| BDNF | SHC1 | ENSCSAP00000018826 | ENSCSAP00000016061 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | SHC adaptor protein 1. | 0.413 |
| FRS2 | BDNF | ENSCSAP00000000568 | ENSCSAP00000018826 | Fibroblast growth factor receptor substrate 2. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.859 |
| FRS2 | GRB2 | ENSCSAP00000000568 | ENSCSAP00000001067 | Fibroblast growth factor receptor substrate 2. | Growth factor receptor bound protein 2. | 0.997 |
| FRS2 | NGF | ENSCSAP00000000568 | ENSCSAP00000017821 | Fibroblast growth factor receptor substrate 2. | Nerve growth factor; Belongs to the NGF-beta family. | 0.581 |
| FRS2 | NTF4 | ENSCSAP00000000568 | ENSCSAP00000019140 | Fibroblast growth factor receptor substrate 2. | Neurotrophin 4; Belongs to the NGF-beta family. | 0.783 |
| FRS2 | NTRK1 | ENSCSAP00000000568 | ENSCSAP00000015828 | Fibroblast growth factor receptor substrate 2. | Tyrosine-protein kinase receptor. | 0.987 |
| FRS2 | PIK3CA | ENSCSAP00000000568 | ENSCSAP00000009123 | Fibroblast growth factor receptor substrate 2. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.826 |
| GRB2 | BDNF | ENSCSAP00000001067 | ENSCSAP00000018826 | Growth factor receptor bound protein 2. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.564 |
| GRB2 | FRS2 | ENSCSAP00000001067 | ENSCSAP00000000568 | Growth factor receptor bound protein 2. | Fibroblast growth factor receptor substrate 2. | 0.997 |
| GRB2 | NTF4 | ENSCSAP00000001067 | ENSCSAP00000019140 | Growth factor receptor bound protein 2. | Neurotrophin 4; Belongs to the NGF-beta family. | 0.582 |
| GRB2 | NTRK1 | ENSCSAP00000001067 | ENSCSAP00000015828 | Growth factor receptor bound protein 2. | Tyrosine-protein kinase receptor. | 0.978 |
| GRB2 | PIK3CA | ENSCSAP00000001067 | ENSCSAP00000009123 | Growth factor receptor bound protein 2. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.947 |