Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHANK1SH3 and multiple ankyrin repeat domains 1. (2173 aa)    
Predicted Functional Partners:
SHANK3
SH3 and multiple ankyrin repeat domains 3.
  
 
0.983
DLGAP1
DLG associated protein 1.
   
 0.968
HOMER1
Homer scaffold protein 1.
    
 0.952
SHANK2
SH3 and multiple ankyrin repeat domains 2.
   
0.939
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.937
LZTS3
Leucine zipper tumor suppressor family member 3.
     
 0.928
DLGAP3
DLG associated protein 3.
   
 0.915
DLGAP2
DLG associated protein 2.
   
 0.896
SHARPIN
SHANK associated RH domain interactor.
    
 0.887
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
   
 0.838
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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