STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNX27Sorting nexin 27. (528 aa)    
Predicted Functional Partners:
VPS26A
VPS26, retromer complex component A.
   
 0.982
VPS26B
VPS26, retromer complex component B.
   
 0.935
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 0.915
OTULIN
OTU deubiquitinase with linear linkage specificity.
    
 
 0.899
SNX1
Sorting nexin 1.
   
 0.829
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 0.829
SNX2
Sorting nexin 2.
   
 0.796
SNX3
Sorting nexin 3.
    
 0.787
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
    
 0.756
SNX6
Sorting nexin 6.
    
 0.742
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.